Scientific Advisor - ADME Project Leadership for Biologics

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: November 3, 2025

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Our diverse ADME team is seeking a dedicated and enthusiastic scientist interested in the discovery and clinical development of medicines across multiple modalities, with a particular emphasis on biologics and drug conjugates. If you have a talent for finding creative solutions to complex problems, apply today! We want you on our team. Our scientifically agile team works collaboratively with biologists, chemists, engineers and various other R&D functions to deliver novel therapies to patients. We support one another through shared-learning and mutual-responsibility for the enterprise of making medicines. Ours is a flexible environment where each team member can optimize their productivity while being mindful of wellness. This enables each of us to grow our careers as well as the scientific field in our search for safe and effective medicines. Please connect with us if you are a motivated and collaborative scientist looking for an opportunity to innovate at the forefront of novel therapies to improve the lives of patients. A high-quality candidate will demonstrate the following: High learning agility and a keen ability to derive and efficiently test ADME and DMPK hypotheses for novel molecules with particular emphasis on antibodies Strong working knowledge in fundamental pharmaceutics, pharmacokinetics and ADME principles especially as they relate to biologics such as antibodies and conjugated molecules Understanding of contemporary pharmaceutical regulatory guidance and expectations Skills to integrate internal and external laboratory and other experimental resources through high quality scientific associations Agile interrogation of diverse data (e.g., in silico, in vitro, in vivo) to derive mechanistic understanding of drug action and performance characteristics Lilly-ADME seeks a skilled ADME / DMPK scientist who will: Lead and innovate in a multidisciplinary collaborative environment with primary responsibility for ADME studies to support preclinical and clinical development of the Lilly portfolio Design and implement hypothesis driven studies to answer ADME, PK/PD and clinical pharmacology questions Integrate ADME, PK and PK/PD endpoints with discovery biology data to define structure activity- and structure-property-relationships to guide drug delivery and optimization strategies Engage, innovate, and collaborate with colleagues and interdisciplinary teams Lead the preparation of regulatory communication and documents to support clinical development, new drug applications (NDA and BLA) and line extensions and interact with regulatory agencies worldwide Build and foster relationships through coaching and mentorship with fellow scientists Possess excellent written and verbal technical communication skills and the ability to lead, guide and influence teams in decision making Location: Onsite presence (minimum of 3 days/week) at either our headquarters in Indianapolis, Indiana, or our Harborside location in Boston, Massachusetts Basic Requirements: Ph.D. in Biology, Cellular or Molecular Biology, Biochemistry, Pharmaceutical Sciences, Pharmacokinetics or a related scientific field; experience in the discovery and development of biological-therapeutics highly preferred Additional Skills/Preferences: Industry (Pharma/Biotech) experience (1- 7 years) in the preclinical evaluation of biologics and or hybrid modalities, as well as relevant ADME project leadership experience Understanding of and experience with immunoassays, and/or LC/MS bioanalytical methodology Detailed understanding of pharmacokinetics, ADME and proficiency to communicate theory and concepts clearly Experience in drug discovery and development Experience with PK/PD modeling and/or bio-distribution Ability to balance multiple projects and handle competing responsibilities Collaborative team behaviors and aspiration to build and sustain relationships with R&D customers and the wider scientific community Excellent oral and written communication skills Experience authoring regulatory and technical reports Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $151,500 - $244,200 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

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