Lead Site Reliability Engineer (SRE)

Location: Indianapolis
Posted on: June 23, 2025

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Come tackle complex challenges and ensure the reliability of critical applications to help patients! Lilly’s Software Product Engineering team is actively looking for a Lead Site Reliability Engineer (SRE). Are you ready to own and complete complicated and technically ambitious tasks? Are you passionate about technology with extensive experience in observability, AWS, Kubernetes, and DevOps practices? If so, please apply. What You’ll Be Doing: Ensure the health and performance of applications by setting up state-of-the-art monitoring tools, creating proactive alerting systems, analyzing incident data, and enhancing defect observability. Implement AI-driven operations to enhance system performance and reliability. Lead design reviews with peers and stakeholders to select the best available technologies, conduct thorough performance testing, and analyze performance metrics. Develop robust scripts and automation tools, creating self-healing mechanisms, and integrating new tools to enhance system resilience. Utilize advanced analytics to predict and prevent potential issues before they impact application performance. Collaborate with development, operations, and other teams to ensure smooth and efficient application operations. Respond to incidents and managing them using ITIL processes. Forecast resource needs, optimizing system performance, and providing 24/7 global coverage to ensure uninterrupted application operations. How You’ll Succeed: Standardizing best practices and scaling them across all supported applications. Continuously identify potential issues before they become critical and implement preventive measures to mitigate risks. Regularly review and refine processes, tools, and systems to ensure they are up-to-date and optimized for performance and reliability. Maintain clear and open communication channels with all stakeholders, ensuring everyone is informed about the status of applications and any incidents that occur. Provide guidance and training to junior team members, helping them develop their skills and knowledge in site reliability engineering. Stay current with industry trends and emerging technologies and be willing to adapt and innovate to improve application reliability and performance. Always prioritize the needs and experiences of end-users, ensuring that applications are reliable, efficient, and user-friendly. What You Should Bring: Extensive observability background, OpenTelemetry, AWS knowledge, Kubernetes, DevOps practices, monitoring tools (Splunk, AppDynamics, Datadog), scripting (Python), L1 & L2 support, incident management, ITIL, and documentation skills. Experience with disaster recovery, business continuity planning, creating ServiceNow dashboards, Linux, and shell scripting. Good-to-have skills and certifications: ITIL Foundation certification, AWS or other Cloud Certification(s), SQL, Postman, MuleSoft, and networking concepts. Basic Requirements: A Bachelor's or Master's degree in Computer Science, Engineering, or a related technical field, plus a minimum of 6 years of experience as an SRE or similar OR a high school diploma/GED plus 8 years experience as an SRE or similar. ?Qualified US candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position. Additional Information Position based in Indianapolis, Indiana with a hybrid work model. About the Organization Tech @ Lilly builds and maintains capabilities using groundbreaking technologies like most prominent tech companies. What differentiates Tech @ Lilly is that we create new possibilities through tech to advance our purpose – creating medicines that make life better for people around the world, like data driven drug discovery and connected clinical trials. We hire the best technology professionals from a variety of backgrounds, so they can bring an assortment of knowledge, skills, and diverse thinking to deliver innovative solutions in every area of our business. Lilly’s Software Product Engineering (SPE) organization is focused on building core foundational software platforms to accelerate our ability to reach and support patients, digitally. This organization is powered by software engineering experts that solve challenging problems around patient engagement and drug discovery with code. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $123,000 - $180,400 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

Keywords: , Indianapolis , Lead Site Reliability Engineer (SRE), IT / Software / Systems , Indianapolis, Indiana